| Identification | Back Directory | [Name]
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL | [CAS]
220641-87-2 | [Synonyms]
CHEMBRDG-BB 4003545
N-Methyloxan-4-aMine
4-(MethylaMino)tetrahydropyran
4-(Methylamino)tetrahydro-2H-pyran
N-METHYL-TETRAHYDRO-2H-PYRAN-4-AMINE
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE
tetrahydro-N-Methyl-2H-pyran-4-aMine
2H-Pyran-4-amine,tetrahydro-N-methyl-
N-Methyltetrahydro-2H-pyran-4-ylamine
N-Methyl-N-(tetrahydropyran-4-yl)amine
4-(Methylamino)tetrahydro-2H-pyran 95%
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL
N-METHYL-N-TETRAHYDRO-2H-PYRAN-4-YLAMINE
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HYDROCHLORIDE
N-METHYL-TETRAHYDRO-2H-PYRAN-4-AMINE HYDROCHLORIDE
tetrahydro-N-methyl-2H-pyran-4-amine hydrochloride
N-methyltetrahydro-2H-pyran-4-amine(SALTDATA: FREE)
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL###220641-87-2
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL ISO 9001：2015 REACH
(4-Aminophenyl)Boronic Acid Hydrochloride (1:1)
(4AMINOPHENYL)BORONIC ACID HCl | [EINECS(EC#)]
205-516-1 | [Molecular Formula]
C6H13NO | [MDL Number]
MFCD06738977 | [MOL File]
220641-87-2.mol | [Molecular Weight]
115.17 |
| Chemical Properties | Back Directory | [Boiling point ]
165.0±33.0 °C(Predicted) | [density ]
0.93±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Inert atmosphere,2-8°C | [form ]
liquid | [pka]
10.01±0.20(Predicted) | [color ]
Clear, colourless |
| Hazard Information | Back Directory | [Uses]
Methyl-(Tetrahydro-Pyran-4-Yl)-Amine Hcl is mainly used in dyes, pesticides, etc., but also food additives, flavours, and fragrances.
| [Synthesis]
To a stirred solution of tetrahydro-4H-pyran-4-one (1 g, 10 mmol) in tetrahydrofuran (THF, 10 mL) was added slowly and dropwise at room temperature methylamine (0.62 g, 20 mmol, 2 M THF solution), followed by acetic acid (0.5 mL). The reaction mixture was stirred continuously for 1 hour. Subsequently, sodium cyanoborohydride (0.7 g, 12 mmol) was added to the reaction mixture at 0 °C and stirring was continued for 16 h at room temperature. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm the completion of the reaction. Eventually, the target product N-methyltetrahydro-2H-pyran-4-amine (1 g) was isolated as a yellow liquid. Mass spectrum (ESI) m/z 115 [M]+. | [References]
[1] Patent: US2016/289171, 2016, A1. Location in patent: Paragraph 1794
[2] Patent: US2017/348315, 2017, A1. Location in patent: Paragraph 0322 |
|
|