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220641-87-2

220641-87-2 Structure

220641-87-2 Structure
IdentificationBack Directory
[Name]

METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL
[CAS]

220641-87-2
[Synonyms]

CHEMBRDG-BB 4003545
N-Methyloxan-4-aMine
4-(MethylaMino)tetrahydropyran
4-(Methylamino)tetrahydro-2H-pyran
N-METHYL-TETRAHYDRO-2H-PYRAN-4-AMINE
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE
tetrahydro-N-Methyl-2H-pyran-4-aMine
2H-Pyran-4-amine,tetrahydro-N-methyl-
N-Methyltetrahydro-2H-pyran-4-ylamine
N-Methyl-N-(tetrahydropyran-4-yl)amine
4-(Methylamino)tetrahydro-2H-pyran 95%
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL
N-METHYL-N-TETRAHYDRO-2H-PYRAN-4-YLAMINE
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HYDROCHLORIDE
N-METHYL-TETRAHYDRO-2H-PYRAN-4-AMINE HYDROCHLORIDE
tetrahydro-N-methyl-2H-pyran-4-amine hydrochloride
N-methyltetrahydro-2H-pyran-4-amine(SALTDATA: FREE)
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL###220641-87-2
METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL ISO 9001:2015 REACH
(4-Aminophenyl)Boronic Acid Hydrochloride (1:1) (4AMINOPHENYL)BORONIC ACID HCl
[EINECS(EC#)]

205-516-1
[Molecular Formula]

C6H13NO
[MDL Number]

MFCD06738977
[MOL File]

220641-87-2.mol
[Molecular Weight]

115.17
Chemical PropertiesBack Directory
[Boiling point ]

165.0±33.0 °C(Predicted)
[density ]

0.93±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,2-8°C
[form ]

liquid
[pka]

10.01±0.20(Predicted)
[color ]

Clear, colourless
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P305+P351+P338
[Hazard Codes ]

Xi,Xn
[Risk Statements ]

36/37/38-22
[Safety Statements ]

26-36/37/39
[RIDADR ]

UN2735
[Hazard Note ]

Harmful
[HazardClass ]

IRRITANT
[HS Code ]

2932990090
Hazard InformationBack Directory
[Uses]

Methyl-(Tetrahydro-Pyran-4-Yl)-Amine Hcl is mainly used in dyes, pesticides, etc., but also food additives, flavours, and fragrances.
[Synthesis]

Tetrahydro-4H-pyran-4-one

29943-42-8

Methylamine

74-89-5

Methyl-(Tetrahydro-Pyran-4-Yl)-Amine Hcl

220641-87-2

To a stirred solution of tetrahydro-4H-pyran-4-one (1 g, 10 mmol) in tetrahydrofuran (THF, 10 mL) was added slowly and dropwise at room temperature methylamine (0.62 g, 20 mmol, 2 M THF solution), followed by acetic acid (0.5 mL). The reaction mixture was stirred continuously for 1 hour. Subsequently, sodium cyanoborohydride (0.7 g, 12 mmol) was added to the reaction mixture at 0 °C and stirring was continued for 16 h at room temperature. The progress of the reaction was monitored by thin layer chromatography (TLC) to confirm the completion of the reaction. Eventually, the target product N-methyltetrahydro-2H-pyran-4-amine (1 g) was isolated as a yellow liquid. Mass spectrum (ESI) m/z 115 [M]+.

[References]

[1] Patent: US2016/289171, 2016, A1. Location in patent: Paragraph 1794
[2] Patent: US2017/348315, 2017, A1. Location in patent: Paragraph 0322
Spectrum DetailBack Directory
[Spectrum Detail]

METHYL-(TETRAHYDRO-PYRAN-4-YL)-AMINE HCL(220641-87-2)1HNMR
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