| Chemical Properties | Back Directory | [Melting point ]
255-257 °C (decomp)(Solv: ethanol (64-17-5); ligroine (8032-32-4)) | [Boiling point ]
753.9±60.0 °C(Predicted) | [density ]
1.33±0.1 g/cm3(Predicted) | [pka]
9.00±0.40(Predicted) |
| Hazard Information | Back Directory | [Uses]
Silatecan (AR-67; DB 67) is a Camptothecin (HY-16560) analogue with improved stability and lipophilicity. Silatecan is an inhibitor for topoisomerase I, that inhibits the DNA replication and transcription, and exhibits antitumor and radiosensitizing activities[1] | [IC 50]
Topoisomerase I | [References]
[1] Chen A Y, et al. Silatecan DB-67 is a novel DNA topoisomerase I–targeted radiation sensitizer[J]. Molecular cancer therapeutics, 2005, 4(2): 317-324. |
|
| Company Name: |
NCE Biomedical Co.,Ltd.
|
| Tel: |
4000-027-021 |24 +86-13986109188 | +86-15623472865 | +81-08033611988 |
| Website: |
www.chemicalbook.com/ShowSupplierProductsList15748/0_EN.htm |
| Company Name: |
SPIRO PHARMA
|
| Tel: |
|
| Website: |
www.spiropharma.com.cn |
| Company Name: |
BOC Sciences
|
| Tel: |
16314854226 |
| Website: |
www.bocsci.com |
|