| Identification | Back Directory | [Name]
2-METHYLTHIOADENOSINE 5-MONOPHOSPHATE | [CAS]
22140-20-1 | [Synonyms]
2-mesamp 2-MeS-5'-AMP 2-Methylthio-AMP 2MESAMP , CID189762 2-Methylthio-AMP TEA salt 5'-Adenylic acid, 2-(methylthio)- 2-METHYLTHIOADENOSINE 5-MONOPHOSPHATE 2-Methylthio-AMP triethylammonium salt hydrate 2-MeSAMP, 2-Methylthio-AMP hydrate triethylammonium salt 2-methylthioadenosine 5'-monophosphate triethylammonium salt hydrate 2-Methylthioadenosine 5μ-monophosphate hydrate triethylammonium salt | [Molecular Formula]
C11H16N5O7PS | [MDL Number]
MFCD07779401 | [MOL File]
22140-20-1.mol | [Molecular Weight]
393.31 |
| Chemical Properties | Back Directory | [storage temp. ]
−20°C | [solubility ]
H2O: soluble20mg/mL, clear, colorless | [form ]
solid | [color ]
white | [Water Solubility ]
H2O: 20mg/mL, clear, colorless | [InChIKey]
YQMUWWZKFZERBT-IDIVVRGQSA-N | [SMILES]
O.CCN(CC)CC.CSc1nc(N)c2ncn([C@@H]3O[C@H](COP(O)(O)=O)[C@@H](O)[C@H]3O)c2n1 |
| Hazard Information | Back Directory | [Uses]
2-Methylthioadenosine 5μ-monophosphate triethylammonium salt hydrate has been used:
- as a P2Y12 inhibitor to study its effects on stimulation of endocytosis in high-density lipoprotein (HDL).
- as a P2Y12 inhibitor to study its effects on platelet recruitment in whole human blood.
| [Biochem/physiol Actions]
The only known preferential antagonist for P2Y(AC) receptor; this is the platelet ADP receptor that is coupled to adenyl cyclase and is also referred to as the P2Y ADP receptor. |
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