ChemicalBook--->CAS DataBase List--->2215022-45-8

2215022-45-8

2215022-45-8 Structure

2215022-45-8 Structure
IdentificationBack Directory
[Name]

AZD8154
[CAS]

2215022-45-8
[Synonyms]

AZD8154
[Molecular Formula]

C27H29N5O4S2
[MOL File]

2215022-45-8.mol
[Molecular Weight]

551.68
Chemical PropertiesBack Directory
[Boiling point ]

898.9±75.0 °C(Predicted)
[density ]

1.437±0.06 g/cm3(Predicted)
[storage temp. ]

Store at -20°C
[solubility ]

DMSO : 25 mg/mL (45.32 mM; Need ultrasonic)
[form ]

Solid
[pka]

2.82±0.10(Predicted)
[color ]

Light yellow to yellow
Hazard InformationBack Directory
[Uses]

AZD8154 is a novel inhaled selective PI3Kγδ dual inhibitor targeting airway inflammatory disease.
[IC 50]

PI3Kγ
[storage]

Store at -20°C
[References]

[1] Sadiq MW, et al. Characterisation of pharmacokinetics, safety and tolerability in a first-in-human study for AZD8154, a novel inhaled selective PI3Kγδ dual inhibitor targeting airway inflammatory disease. Br J Clin Pharmacol. 2021 Jun 28. DOI:10.1111/bcp.14956
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