ChemicalBook--->CAS DataBase List--->221681-92-1

221681-92-1

221681-92-1 Structure

221681-92-1 Structure
IdentificationBack Directory
[Name]

1,3-DiMethyl-6-aMino-1H-indazole
[CAS]

221681-92-1
[Synonyms]

Pazopanib Impurity 17
1,3-Dimethylindazol-6-amine
1,3-DiMethyl-6-aMino-1H-i...
1,3-dimethyl-1H-indazol-6-amine
1,3-DiMethyl-6-aMino-1H-indazole
1H-Indazol-6-amine, 1,3-dimethyl-
1,3-Dimethyl-1H-indazol-6-ylamine
[Molecular Formula]

C9H11N3
[MDL Number]

MFCD18432764
[MOL File]

221681-92-1.mol
[Molecular Weight]

161.2
Chemical PropertiesBack Directory
[Boiling point ]

335.4±22.0 °C(Predicted)
[density ]

1.23±0.1 g/cm3(Predicted)
[storage temp. ]

Keep in dark place,Inert atmosphere,Room temperature
[pka]

3.93±0.50(Predicted)
[Appearance]

light yellow solid
Safety DataBack Directory
[Symbol(GHS) ]

Exclamation Mark (GHS07)
GHS07
[Signal word ]

Warning
[Hazard statements ]

H302-H315-H320-H335
[Precautionary statements ]

P261-P280-P301+P312-P302+P352-P305+P351+P338
Hazard InformationBack Directory
[Uses]

1,3-dimethyl-1H-indazol-6-amine is an impurity in the synthesis of Pazopanib (P210925) which is an oral angiogenesis inhibitor targeting VEGFR and PDGFR. It is used as a reagent in the preparation of glycinamide derivatives which are useful in production of drugs for preventing and treating diseases caused by S-adenosyl homocysteine hydrolase.
Spectrum DetailBack Directory
[Spectrum Detail]

1,3-DiMethyl-6-aMino-1H-indazole(221681-92-1)1HNMR
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