| Identification | Back Directory | [Name]
1-Cyclohexene-1-carboxamide, 4-(acetylamino)-5-amino-N-[[1-[(4-bromophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3-(1-ethylpropoxy)-, (3R,4R,5S)- | [CAS]
2217630-64-1 | [Synonyms]
Neuraminidase-IN-9
1-Cyclohexene-1-carboxamide, 4-(acetylamino)-5-amino-N-[[1-[(4-bromophenyl)methyl]-1H-1,2,3-triazol-4-yl]methyl]-3-(1-ethylpropoxy)-, (3R,4R,5S)- | [Molecular Formula]
C24H33BrN6O3 | [MOL File]
2217630-64-1.mol | [Molecular Weight]
533.46 |
| Hazard Information | Back Directory | [Uses]
Neuraminidase-IN-9 (Compound 6l) is a potent influenza neuraminidase inhibitor with IC50 values of 0.12, 0.049 and 0.16 μM against H5N1, H5N2 and H5N6, respectively[1]. | [References]
[1] Ju H, et al. Discovery of novel 1,2,3-triazole oseltamivir derivatives as potent influenza neuraminidase inhibitors targeting the 430-cavity. Eur J Med Chem. 2020 Feb 1;187:111940. DOI:10.1016/j.ejmech.2019.111940 |
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