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2218484-75-2

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2218484-75-2 Structure

2218484-75-2 Structure

Identification	Back Directory
[Name] PF-06815189
[CAS] 2218484-75-2
[Synonyms] PF-06815189 Imidazo[5,1-f][1,2,4]triazin-4(1H)-one, 7-[1,3-dimethyl-5-[4-(trifluoromethyl)phenyl]-1H-pyrazol-4-yl]-5-(hydroxymethyl)-2-methyl-
[Molecular Formula] C19H17F3N6O2
[MOL File] 2218484-75-2.mol
[Molecular Weight] 418.37

Chemical Properties	Back Directory
[Boiling point ] 621.2±65.0 °C(Predicted)
[density ] 1.54±0.1 g/cm3(Predicted)
[pka] 12.89±0.10(Predicted)

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[Uses] PF-06815189 is a phosphodiesterase 2A (PDE2A) inhibitor with an IC50 of 0.4 nM[1].
[IC 50] PDE2A: 0.4 nM (IC₅₀)
[References] [1] Stepan AF, et al. Late-Stage Microsomal Oxidation Reduces Drug-Drug Interaction and Identifies Phosphodiesterase 2A Inhibitor PF-06815189. ACS Med Chem Lett. 2018 Jan 4;9(2):68-72. DOI:10.1021/acsmedchemlett.7b00343

2218484-75-2 suppliers list

Company Name:	Suzhou youruike Chemical Pharmaceutical Technology Co., Ltd
Tel:	15317229551
Website:	https://www.ureiko.com

Company Name:	TargetMol Chemicals Inc.
Tel:	15002134094
Website:	https://www.targetmol.cn/

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