| Identification | Back Directory | [Name]
TZ3O | [CAS]
2218754-19-7 | [Synonyms]
TZ3O
2,4-Thiazolidinedione, 5-[(3-hydroxyphenyl)methylene]-3-(2-oxo-2-phenylethyl)- | [Molecular Formula]
C18H13NO4S | [MOL File]
2218754-19-7.mol | [Molecular Weight]
339.37 |
| Chemical Properties | Back Directory | [Boiling point ]
574.2±60.0 °C(predicted) | [density ]
1.441±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
9.22±0.10(predicted) |
| Hazard Information | Back Directory | [Uses]
(Rac)-TZ3O is the (Rac) isomer of TZ3O. TZ3O is an anticholinergic compound with neuroprotective activity. TZ3O improves memory impairment and cognitive decline in a scopolamine-induced Alzheimer's disease rat model and can be used in the study of Alzheimer's disease. | [References]
[1] Taheri M, et al. Neuroprotective Effect of Thiazolidine-2,4-dione Derivatives on Memory Deficits and Neuropathological Symptoms of Dementia on a Scopolamine-Induced Alzheimer's Model in Adult Male Wistar Rats. ACS Chem Neurosci. 2023 Sep 6;14(17):3156-3172. |
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