| Identification | Back Directory | [Name]
N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine 1,1'-bis[2-(octyloxy)ethyl] ester | [CAS]
222315-88-0 | [Synonyms]
N,N'-[1,2-Ethanediylbis(oxy-2,1-phenylene)]bis[N-(carboxymethyl)glycine 1,1'-bis[2-(octyloxy)ethyl] ester | [Molecular Formula]
C42H64N2O12 | [MOL File]
222315-88-0.mol | [Molecular Weight]
788.96 |
| Chemical Properties | Back Directory | [Melting point ]
121-122 °C | [Boiling point ]
864.8±65.0 °C(Predicted) | [density ]
1.161 | [form ]
Solid | [pka]
2.00±0.10(Predicted) | [color ]
White to light yellow |
| Hazard Information | Back Directory | [Uses]
DP-b99 is a chelator of zinc and calcium ions that acts selectively within cell membranes and has neuroprotective properties in animal models of stroke. | [References]
[1] Kalendarev T, Zupkovitz G, Ioffe V. The unusual gradient elution for reversed phase HPLC of a strong chelator as an active drug substance. J Pharm Biomed Anal. 2001;24(5-6):967-975. DOI:10.1016/s0731-7085(00)00567-7
[2] Diener HC, Schneider D, Lampl Y, Bornstein NM, Kozak A, Rosenberg G. DP-b99, a membrane-activated metal ion chelator, as neuroprotective therapy in ischemic stroke. Stroke. 2008;39(6):1774-1778. DOI:10.1161/STROKEAHA.107.506378 |
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