| Hazard Information | Back Directory | [Uses]
NBI-961 is a potent NEK2 inhibitor that inhibits proteasomal degradation. NBI-961 induces G2/mitosis arrest and apoptosis in diffuse large B cell lymphoma (DLBCL) cells[1]. | [IC 50]
NEK2 | [References]
[1] Mason McCrury, et al. Bifunctional inhibitor reveals NEK2 as a therapeutic target and regulator of oncogenic pathways in lymphoma. Mol Cancer Ther. 2023 Oct 11. DOI:10.1158/1535-7163.MCT-23-0299 |
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