| Identification | Back Directory | [Name]
MNI-caged-L-glutamate (trifluoroacetate salt) | [CAS]
2226362-29-2 | [Synonyms]
MNI-caged-L-glutamate (trifluoroacetate salt) | [Molecular Formula]
C16H18F3N3O8 | [MOL File]
2226362-29-2.mol | [Molecular Weight]
437.33 |
| Hazard Information | Back Directory | [Description]
MNI-caged-L-glutamate is a form of glutamate linked to a 4-methoxy-7-nitroindolinyl (MNI) photoprotecting group that is pharmacologically inactive at neuronal glutamate receptors (up to mM concentrations). Upon exposure to light (300 - 380 nm excitation), L-glutamate is cleaved of MNI and released within submicroseconds. This compound can be used to investigate the mechanisms of fast synaptic glutamate receptors in situ. | [Uses]
MNI-caged-L-glutamate TFA is a reagent that can release neuroactive amino acids quickly and efficiently[1]. | [storage]
Store at -20°C | [References]
[1] Canepari M, et al. Photochemical and pharmacological evaluation of 7-nitroindolinyl-and 4-methoxy-7-nitroindolinyl-amino acids as novel, fast caged neurotransmitters. J Neurosci Methods. 2001 Nov 15;112(1):29-42. DOI:10.1016/s0165-0270(01)00451-4 |
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