2226733-37-3

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2226733-37-3 Structure

Identification	Back Directory
[Name] Mal-PEG24-NHS ester
[CAS] 2226733-37-3
[Synonyms] Mal-PEG24-NHS ester BMPA-PEG24-NHS Ester Maleimide-PEG24-NHS Ester 4,7,10,13,16,19,22,25,28,31,34,37,40,43,46,49,52,55,58,61,64,67,70,73-Tetracosaoxa-76-azanonaheptacontanoic acid, 79-(2,5-dihydro-2,5-dioxo-1H-pyrrol-1-yl)-77-oxo-, 2,5-dioxo-1-pyrrolidinyl ester (2,5-dioxopyrrolidin-1-yl) 3-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[2-[3-(2,5-dioxopyrrol-1-yl)propanoylamino]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]propanoate
[Molecular Formula] C62H111N3O31
[MDL Number] MFCD11041160
[MOL File] 2226733-37-3.mol
[Molecular Weight] 1394.55

Chemical Properties	Back Directory
[density ] 1.23±0.1 g/cm3(Predicted)
[form ] Oil
[pka] 15.01±0.46(Predicted)
[color ] Colorless to light yellow

Hazard Information	Back Directory
[Uses] Mal-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1].
[IC 50] PEGs
[References] [1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562. DOI:10.1016/j.ebiom.2018.09.005

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