| Identification | Back Directory | [Name]
Olean-12-en-29-oic acid, 3-[4-[(6-fluoro-2-benzothiazolyl)amino]-1,4-dioxobutoxy]-11-oxo-, ethyl ester, (3β,20β)- | [CAS]
2227303-22-0 | [Synonyms]
HSP90-CDC37-IN-1
Olean-12-en-29-oic acid, 3-[4-[(6-fluoro-2-benzothiazolyl)amino]-1,4-dioxobutoxy]-11-oxo-, ethyl ester, (3β,20β)- | [Molecular Formula]
C43H57FN2O6S | [MDL Number]
MFCD31813636 | [MOL File]
2227303-22-0.mol | [Molecular Weight]
748.99 |
| Hazard Information | Back Directory | [Uses]
Hsp90-Cdc37-IN-1 is an Hsp90-Cdc37 interaction disruptor that inhibit cell migration and reverse agent resistance, with an IC50 of 140 nM. | [References]
[1] Jin L, et al. Discovery of 18β-glycyrrhetinic acid conjugated aminobenzothiazole derivatives as Hsp90-Cdc37 interaction disruptors that inhibit cell migration and reverse drug resistance. Bioorg Med Chem. 2018 May 1;26(8):1759-1775. DOI:10.1016/j.bmc.2018.02.021 |
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