| Identification | Back Directory | [Name]
RasGRP3 ligand 96 | [CAS]
2229068-13-5 | [Synonyms]
RasGRP3 ligand 96 Propanoic acid, 2,2-dimethyl-, [(4E)-tetrahydro-2-(hydroxymethyl)-4-[(1-methyl-1H-indol-3-yl)methylene]-5-oxo-2-furanyl]methyl ester | [Molecular Formula]
C21H25NO5 | [MOL File]
2229068-13-5.mol | [Molecular Weight]
371.43 |
| Hazard Information | Back Directory | [Uses]
RasGRP3 ligand 1 (compound 96) is a RasGRP3 ligand with a Ki of 1.75 nM. RasGRP3 ligand 1 can induce Ras activation and can be used for cancer research[1]. | [References]
[1] Ann J, et al. α-Arylidene Diacylglycerol-Lactones (DAG-Lactones) as Selective Ras Guanine-Releasing Protein 3 (RasGRP3) Ligands. J Med Chem. 2018 Jul 26;61(14):6261-6276. DOI:10.1021/acs.jmedchem.8b00661 |
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