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Revdofilimab (ABBV-368) is a human IgG1 agonist monoclonal antibody against OX40. Among them, OX40 is a member of the TNF receptor superfamily expressed on activated and memory T cell subsets and T regulatory cells[1]. | [References]
[1] A. Spira, et al. Safety, tolerability, and pharmacokinetics of the OX40 agonist ABBV-368 in patients with advanced solid tumors. ABSTRACTS IMMUNOTHERAPY OF CANCER|?VOLUME 29, SUPPLEMENT 8,?VIII409,?OCTOBER 2018 |
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