| Identification | Back Directory | [Name]
Arborcandin E | [CAS]
223465-80-3 | [Synonyms]
Arborcandin E
Cyclo(β-alanyl-2-amino-10-hydroxyhexadecanoyl-D-asparaginyl-L-asparaginyl-D-alanyl-4-hydroxyglutaminyl-D-allothreonyl-L-threonyl-2-amino-5-hydroxypentadecanoylglycyl)
Cyclo(β-alanyl-2-amino-10-hydroxyhexadecanoyl-D-asparaginyl-L-asparaginyl-D-alanyl-4-hydroxyglutaminyl-D-allothreonyl-L-threonyl-2-amino-5-hydroxypentadecanoylglycyl) (9CI) | [Molecular Formula]
C60H107N13O18 | [MOL File]
223465-80-3.mol | [Molecular Weight]
1298.57 |
| Hazard Information | Back Directory | [Uses]
Arborcandin E is a 1,3-β-glucan synthase inhibitor that serves as an antifungal antibiotic. Arborcandin E exhibits IC50 values of 0.1 μg/mL and 0.012 μg/mL against Candida albicans and Aspergillus fumigatus, respectively. Additionally, Arborcandin E has an MIC of 0.5-2 μg/mL against the genus Candida[1]. | [References]
[1] Ohyama T, et al. Arborcandins A, B, C, D, E and F, novel 1, 3-β-glucan synthase inhibitors: Production and biological activity[J]. The Journal of Antibiotics, 2000, 53(10): 1108-1116. DOI:10.7164/antibiotics.53.1108 |
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