| Identification | Back Directory | [Name]
(Z-ASP-GLU-VAL-ASP)2-RHODAMINE 110 | [CAS]
223538-61-2 | [Synonyms]
(Z-DEVD)2-R110
(Z-DEVD)2-RhodaMine 110
(Z-ASP-GLU-VAL-ASP)2-RHODAMINE 110
4,4'-[9-(2-Carboxyphenyl)xanthylium-3,6-diyl]bis[N-[(phenylmethoxy)carbonyl]-L-alpha-aspartyl-L-alpha-glutamyl-L-valyl-L-alpha-asparagine inner salt | [Molecular Formula]
C72H78N10O27 | [MDL Number]
MFCD08702756 | [MOL File]
223538-61-2.mol | [Molecular Weight]
1515.46 |
| Hazard Information | Back Directory | [Uses]
Z-DEVD-R110 ((Z-Asp-Glu-Val-Asp)2-Rhodamine 110) is a fluorogenic caspase-3/7 substrate. Z-DEVD-R110 can be used to detect apoptosis. Z-DEVD-R110 is a rhodamine derivative with two four–amino acid (DEVD) peptides linked to the fuorophore[1]. | [References]
[1] Cheng X, et al. Apoptosis propagates through the cytoplasm as trigger waves. Science. 2018 Aug 10;361(6402):607-612. DOI:10.1126/science.aah4065 |
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