| Chemical Properties | Back Directory | [storage temp. ]
2-8°C | [form ]
powder | [Appearance]
White to off-white Solid | [InChI]
1S/C12H18N2.2ClH/c13-9-11-3-1-2-4-12(11)10-5-7-14-8-6-10;;/h1-4,10,14H,5-9,13H2;2*1H | [InChIKey]
VBWHHONSCAVPOS-UHFFFAOYSA-N | [SMILES]
NCC1=C(C=CC=C1)C2CCNCC2.Cl.Cl |
| Hazard Information | Back Directory | [Uses]
(2-(Piperidin-4-yl)phenyl)methanamine dihydrochloride is a 4-aryl piperidine useful as a semi-flexible linker in PROTAC development for targeted protein degradation. Incorporation of rigidity into the linker region of bifunctional protein degraders may impact the 3D orientation of the degrader and thus ternary complex formation as well as optimization of drug-like properties. | [reaction suitability]
reagent type: linker |
|
| Company Name: |
TaiChem Taizhou Limited
|
| Tel: |
052386810091 |
| Website: |
https://www.chemicalbook.com/supplier/11410902/1.htm |
| Company Name: |
Merck KGaA
|
| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
|