ChemicalBook--->CAS DataBase List--->2245697-83-8

2245697-83-8

2245697-83-8 Structure

2245697-83-8 Structure
IdentificationBack Directory
[CAS]

2245697-83-8
[Molecular Formula]

C27H40ClN5O4S
[Molecular Weight]

566.16
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

Light yellow to green yellow
Hazard InformationBack Directory
[Uses]

(S,R,S)-AHPC-C4-NH2 hydrochloride is a synthesized E3 ligase ligand-linker conjugate that incorporates the (S,R,S)-AHPC based VHL ligand and a linker used for EED-Targeted PROTAC[1].
[IC 50]

VHL
[References]

[1] Hsu JH, et al. EED-Targeted PROTACs Degrade EED, EZH2, and SUZ12 in the PRC2 Complex. Cell Chem Biol. 2019 Nov 26. pii: S2451-9456(19)30362-9. DOI:10.1016/j.chembiol.2019.11.004
Spectrum DetailBack Directory
[Spectrum Detail]

Protac linker 5(2245697-83-8)1HNMR
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