2245698-48-8

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2245698-48-8 Structure

Identification	Back Directory
[Name] DM4-SPDP
[CAS] 2245698-48-8
[Synonyms] DM4-SPDP Maytansine, N2'-deacetyl-N2'-[4-[[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropyl]dithio]-4-methyl-1-oxopentyl]-
[Molecular Formula] C45H61ClN4O14S2
[MDL Number] MFCD28400105
[MOL File] 2245698-48-8.mol
[Molecular Weight] 981.57

Hazard Information	Back Directory
[Uses] (R)-DM4-SPDP is a conjugate made up of the linker SPDP and the toxic molecule DM4, and it can be used to prepare antibody-drug conjugates[1].
[storage] Store at -20°C
[References] [1] Silvana T Tivadar, et al. Monoclonal Antibody Targeting Sialyl-di-Lewisa-Containing Internalizing and Noninternalizing Glycoproteins with Cancer Immunotherapy Development Potential. Mol Cancer Ther. 2020 Mar;19(3):790-801. DOI:10.1158/1535-7163.MCT-19-0221

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