ChemicalBook--->CAS DataBase List--->2246956-84-1

2246956-84-1

2246956-84-1 Structure

2246956-84-1 Structure
IdentificationBack Directory
[Name]

CDK9-IN-9
[CAS]

2246956-84-1
[Synonyms]

CDK9-IN-9
[Molecular Formula]

C22H23F2N5O2S
[MDL Number]

MFCD34469559
[MOL File]

2246956-84-1.mol
[Molecular Weight]

459.51
Chemical PropertiesBack Directory
[Boiling point ]

644.7±65.0 °C(Predicted)
[density ]

1.42±0.1 g/cm3(Predicted)
Hazard InformationBack Directory
[Description]

CDK9-IN-9 is a potent and selective CDK9 inhibitor that has has anti-cancer activity.
[Uses]

CDK9-IN-9 (example 2) is a potent and selective CDK9 inhibitor with an IC50 of 1.8 nM. CDK9-IN-9 inhibits CDK2 with an IC50 of 155 nM. CDK9-IN-9 has anti-cancer activity[1].
[IC 50]

CDK9: 1.8 nM (IC50); CDK2: 155 nM (IC50)
[References]

[1] Ulrich LüCKING, et al. Novel ptefb inhibiting macrocyclic compounds. WO2018177889A1.
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