| Identification | Back Directory | [Name]
SGLT inhibitor-1 | [CAS]
2247314-23-2 | [Synonyms]
SGLT inhibitor-1
SGLT inhibitor 1,SGLT inhibitor1
D-Glucitol, 1,5-anhydro-4-deoxy-1-C-[7-[(2,3-dihydro-1,4-benzodioxin-6-yl)methyl]-2,3-dihydro-4-methoxy-5-benzofuranyl]-4-fluoro-, (1S)- | [Molecular Formula]
C24H27FO8 | [MDL Number]
MFCD32067882 | [MOL File]
2247314-23-2.mol | [Molecular Weight]
462.46 |
| Hazard Information | Back Directory | [Uses]
SGLT inhibitor-1 is a potent dual inhibitor of sodium glucose co-transporter proteins (SGLTs), inhibits hSGLT1 and hSGLT2 with IC50s of 43 nM and 9 nM, respectively[1]. | [References]
[1] Xu G， et al. Design, synthesis and biological evaluation of (2S,3R,4R,5S,6R)-5-fluoro-6-(hydroxymethyl)-2-aryltetrahydro-2H-pyran-3,4-diols as potent and orally active SGLT dual inhibitors. Bioorg Med Chem Lett. 2018 Nov 15;28(21):3446-3453. DOI:10.1016/j.bmcl.2018.09.025 |
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cjbscvictory
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13348960310 13348960310 |
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https://www.weikeqi-biotech.com/ |
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