2253640-49-0

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2253640-49-0 Structure

Identification	Back Directory
[Name] PKC-theta inhibitor hcl
[CAS] 2253640-49-0
[Synonyms] PKC-theta inhibitor hcl PKC theta inhibitor hcl,PKCtheta inhibitor hcl
[Molecular Formula] C20H25F3N6O3.ClH
[MOL File] 2253640-49-0.mol
[Molecular Weight] 490.91

Chemical Properties	Back Directory
[storage temp. ] Store at -20°C
[solubility ] DMF: insol,DMSO: 1 mg/ml,Ethanol: insol,PBS (pH 7.2): insol
[form ] A solid

Safety Data	Back Directory
[Symbol(GHS) ] GHS07
[Signal word ] Warning
[Hazard statements ] H315-H319
[Precautionary statements ] P264-P280-P302+P352-P321-P305+P351+P338-P332+P313-P362+P364-P337+P313

Hazard Information	Back Directory
[Uses] PKC-theta inhibitor 2 hydrochloride is a potent and selective PKC-θ inhibitor with an IC50 value of 18 nM[1].
[storage] Store at -20°C
[References] [1] Cywin CL, et al. Discovery of potent and selective PKC-theta inhibitors. Bioorg Med Chem Lett. 2007 Jan 1;17(1):225-30. DOI:10.1016/j.bmcl.2006.09.056

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