| Identification | Back Directory | [Name]
1,2,4-Oxadiazole-5-ethanol, 3-(4-methoxyphenyl)-β-methylene-α-(2-nitrophenyl)- | [CAS]
2253996-75-5 | [Synonyms]
Antiparasitic agent-7
1,2,4-Oxadiazole-5-ethanol, 3-(4-methoxyphenyl)-β-methylene-α-(2-nitrophenyl)- | [Molecular Formula]
C18H15N3O5 | [MOL File]
2253996-75-5.mol | [Molecular Weight]
353.33 |
| Hazard Information | Back Directory | [Uses]
Antiparasitic agent-7 (compound 5d) has selectively antiparasitic activity against Leishmania infantum (L. infantum) with an IC50 value of 2.85 μM. Antiparasitic agent-7 also has certain cytotoxicity against HepG2 (CC50 = 10.61 μM)[1]. | [References]
[1] Fernandes FS, et al. Discovery of highly potent and selective antiparasitic new oxadiazole and hydroxy-oxindole small molecule hybrids. Eur J Med Chem. 2020;201:112418. DOI:10.1016/j.ejmech.2020.112418 |
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