| Identification | Back Directory | [Name]
1H-[1,4]Oxazino[4,3-a]indol-1-one, 3-(2-heptyn-1-ylidene)-3,4-dihydro-10-iodo-, (3E)- | [CAS]
2254751-04-5 | [Synonyms]
UGM-IN-3
1H-[1,4]Oxazino[4,3-a]indol-1-one, 3-(2-heptyn-1-ylidene)-3,4-dihydro-10-iodo-, (3E)- | [Molecular Formula]
C18H16INO2 | [MOL File]
2254751-04-5.mol | [Molecular Weight]
405.24 |
| Hazard Information | Back Directory | [Uses]
UGM-IN-3 (compound 10a) is a UDP-galactopyranose mutase (UGM) inhibitor with a Kd of 66 μM. UGM-IN-3 inhibits the growth of Mycobacterium tuberculosis with a MIC value of 6.2 μg/mL[1]. | [References]
[1] Carine Maaliki, et al. Synthesis and evaluation of heterocycle structures as potential inhibitors of Mycobacterium tuberculosis UGM. Bioorg Med Chem. 2020 Jul 1;28(13):115579. DOI:10.1016/j.bmc.2020.115579 |
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