| Identification | Back Directory | [Name]
ALEXIDINE DIHYDROCHLORIDE | [CAS]
22573-93-9 | [Synonyms]
alexidine
Prestwick_42
Alexidine.2HCl
ALEXIDINE HYDROCHLORIDE
ALEXIDINE DIHYDROCHLORIDE
1,1'-HEXAMETHYLENE-BIS[5-(2-ETHYLHEXYL)BIGUANIDE]
1,1'-Hexamethylene-bis[5-(2-ethylhexyl)biguanide] dihydrochloride | [EINECS(EC#)]
245-096-7 | [Molecular Formula]
C26H58Cl2N10 | [MDL Number]
MFCD00082369 | [MOL File]
22573-93-9.mol | [Molecular Weight]
581.71 |
| Chemical Properties | Back Directory | [Appearance]
White Powder with Light Yellow Cast | [Melting point ]
220-224 | [Boiling point ]
574.5±60.0 °C(Predicted) | [density ]
1.10±0.1 g/cm3(Predicted) | [storage temp. ]
2-8°C | [solubility ]
Methanol (Slightly) | [form ]
Solid | [pka]
12.34±0.10(Predicted) | [color ]
White to Off-White |
| Hazard Information | Back Directory | [Chemical Properties]
White Powder with Light Yellow Cast | [Uses]
Has antibacterial, antiplaque properties against Streptococcus mutans, Actinomyces ciscosus, and Actinomyces naesludii | [Definition]
ChEBI: An amphipathic bisbiguanide with a structure consisting of two (2-ethylhexyl)guanide units linked by a hexamethylene bridge. | [Originator]
Alexidine ,Science Lab. | [Manufacturing Process]
A mixture of 16 g (0.09 mole) 1,1'-hexamethylene-bis(3-cyanoguanidine) and
20 d (0.12 mole) 2-ethylhexylamine hydrochloride is heated at 150-155°C for
3 hours. The mixture is cooled and the product is dissolved in 75 ml of hot
water. The solution is treated with activated charcoal. 1,1'-Hexamethylene-bis-
(5-(ethylhexyl)biguanide) is recrystalluized from methanol-ether, melting point
220.6-223.4°C. | [Therapeutic Function]
Antiseptic |
|
| Company Name: |
Shanghai URChem Limited
|
| Telephone: |
+86-021-50890968，021-50891159 +86-18601776121 |
| Website: |
http://www.urchem.com |
| Company Name: |
Wuhan Topule
|
| Telephone: |
+86-02787215551 19945035818 |
| Website: |
http://www.topule.com/ |
|