| Identification | Back Directory | [Name]
L-Tyrosine, N-[(hexahydro-1H-azepin-1-yl)carbonyl]-L-leucyl-O-(phenylmethyl)-, 1,1-dimethylethyl ester | [CAS]
225925-12-2 | [Synonyms]
PD-151307
L-Tyrosine, N-[(hexahydro-1H-azepin-1-yl)carbonyl]-L-leucyl-O-(phenylmethyl)-, 1,1-dimethylethyl ester | [Molecular Formula]
C33H47N3O5 | [MOL File]
225925-12-2.mol | [Molecular Weight]
565.74 |
| Hazard Information | Back Directory | [Uses]
PD-151307 is an N-type calcium channel antagonist with significant inhibitory effects in IMR-32 human neuroblastoma cells, exhibiting an IC50 of 0.32 μM. PD-151307 can be used in research related to cancer therapy, anticonvulsants, and neuropathic pain[1]. | [References]
[1] Hu LY, et al. N,N-dialkyl-dipeptidylamines as novel N-type calcium channel blockers. Bioorg Med Chem Lett. 1999 Mar 22;9(6):907-12. DOI:10.1016/s0960-894x(99)00100-6 |
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