| Identification | Back Directory | [Name]
3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[1-oxo-9-[3-(4-pentyn-1-yl)-3H-diazirin-3-yl]nonyl]oxy]-, inner salt, 4-oxide, (7R)- | [CAS]
2260670-74-2 | [Synonyms]
3,5,9-Trioxa-4-phosphapentacosan-1-aminium, 4-hydroxy-N,N,N-trimethyl-10-oxo-7-[[1-oxo-9-[3-(4-pentyn-1-yl)-3H-diazirin-3-yl]nonyl]oxy]-, inner salt, 4-oxide, (7R)- | [Molecular Formula]
C39H72N3O8P | [MOL File]
2260670-74-2.mol | [Molecular Weight]
741.99 |
| Hazard Information | Back Directory | [Uses]
1-palmitoyl-2-(9-(3-pent-4-ynyl-3-H-diazirin-3-yl)-nonanoyl)-sn-glycero-3-phosphocholine (16:0-pacFA PC) might be used to label hydrogenated zwitterionic bicelles (HZB) and hydrogenated anionic bicelles (HAB). | [General Description]
The pacFA lipid attached to 1-palmitoyl-sn-glycero-3-phosphocholine, contains a photoactivable diazirine ring with a clickable alkyne group. | [Biochem/physiol Actions]
1-palmitoyl-2-(9-(3-pent-4-ynyl-3-H-diazirin-3-yl)-nonanoyl)-sn-glycero-3-phosphocholine (16:0-pacFA PC) may be used for a global analysis of protein–lipid interactions in living cells. pacFA acts as a precursor for the biosynthesis of bifunctional lipids. Proteins in contact with the bifunctional lipids are then cross-linked by ultraviolet (UV) irradiation of the diazirine ring. Finally, click chemistry is used to label the alkyne with a reporter molecule. |
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| Company Name: |
Merck KGaA
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| Tel: |
21-20338288 |
| Website: |
www.sigmaaldrich.cn |
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