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2268033-83-4

2268033-83-4 Structure

2268033-83-4 Structure
IdentificationBack Directory
[Name]

Phototrexate
[CAS]

2268033-83-4
[Synonyms]

Phototrexate
[Molecular Formula]

C20H19N7O5
[MOL File]

2268033-83-4.mol
[Molecular Weight]

437.42
Chemical PropertiesBack Directory
[solubility ]

Soluble to 4 mM in DMSO
Hazard InformationBack Directory
[Uses]

Phototrexate is a photoswitchable inhibitor of the human dihydrofolate reductase (DHFR). Phototrexate has antifolate and antiproliferative properties, which can be used for the research of cancer[1].
[storage]

Store at -20°C
[References]

[1] Matera C, et al. Photoswitchable Antimetabolite for Targeted Photoactivated Chemotherapy. J Am Chem Soc. 2018 Nov 21;140(46):15764-15773. DOI:10.1021/jacs.8b08249
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