| Identification | Back Directory | [Name]
BIS(DIMETHYLAMINO)METHYLSILANE | [CAS]
22705-33-5 | [Synonyms]
22705-33-5
BIS(DIMETHYLAMINO)METHYLSILANE
N,N,N',N',α-Pentamethylsilanediamine
n,n,n’,n’,1-pentamethyl-silanediamin
N,N,N’,N’,1-pentamethyl-Silanediamine
Silanediamine,N,N,N',N',1-pentamethyl- | [EINECS(EC#)]
245-163-0 | [Molecular Formula]
C5H16N2Si | [MDL Number]
MFCD00048007 | [MOL File]
22705-33-5.mol | [Molecular Weight]
132.28 |
| Chemical Properties | Back Directory | [Melting point ]
<0°C | [Boiling point ]
112 °C | [density ]
0.798 g/mL at 20 °C(lit.) | [refractive index ]
n20/D 1.414 | [Fp ]
-3°C | [pka]
10.24±0.70(Predicted) | [Specific Gravity]
0.798 | [Hydrolytic Sensitivity]
9: reacts extremely rapidly with atmospheric moisture - may be pyrophoric - glove box or sealed system required | [InChI]
InChI=1S/C5H16N2Si/c1-6(2)8(5)7(3)4/h8H,1-5H3 | [InChIKey]
VBYLGQXERITIBP-UHFFFAOYSA-N | [SMILES]
[SiH](C)(N(C)C)N(C)C | [EPA Substance Registry System]
Silanediamine, N,N,N',N',1-pentamethyl- (22705-33-5) |
| Hazard Information | Back Directory | [Description]
Bis(dimethylamino)methylsilane is used as a reagent in the pharmaceutical industry, primarily in silanation reactions. | [Uses]
Bis(dimethylamino)methylsilane can be used as a protecting group for reactive hydrogens in alcohols, amines, thiols, and carboxylic acids. Organosilanes are hydrogen-like, can be introduced in high yield, and can be removed under selective conditions. They are stable over a wide range of reaction conditions and can be removed in the presence of other functional groups, including other protecting groups. |
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