| Identification | Back Directory | [Name]
dl-3-hydroxynorvaline | [CAS]
2280-42-4 | [Synonyms]
beta-Hydroxynorvaline
Norvaline, 3-hydroxy-
3-Hydroxy-DL-norvaline
α-amino-β-hydroxyvaleric acid
2-amino-3-hydroxy-valeric acid
DL-2-Amino-3-hydroxyvaleric acid
DL-3-Hydroxynorvaline >=98% (TLC)
2-azanyl-3-hydroxy-pentanoic acid
α-Amino-β-hydroxyvaleric acid, 2-Amino-3-hydroxypentanoic acid, 3-Hydroxy-2-aminopentanoic acid, DL-β-Hydroxynorvaline | [Molecular Formula]
C5H11NO3 | [MDL Number]
MFCD00010516 | [MOL File]
2280-42-4.mol | [Molecular Weight]
133.15 |
| Chemical Properties | Back Directory | [Melting point ]
231.2℃ | [Boiling point ]
328.4±32.0 °C(Predicted) | [density ]
1.237±0.06 g/cm3(Predicted) | [storage temp. ]
-20°C | [form ]
powder | [pka]
2.39±0.24(Predicted) | [color ]
white | [BRN ]
1722350 | [InChI]
InChI=1S/C5H11NO3/c1-2-3(7)4(6)5(8)9/h3-4,7H,2,6H2,1H3,(H,8,9)/t3?,4-/m0/s1 | [InChIKey]
LGVJIYCMHMKTPB-BKLSDQPFSA-N | [SMILES]
C(O)(=O)[C@H](C(O)CC)N |
| Hazard Information | Back Directory | [Uses]
cell analysis | [Definition]
ChEBI: A non-proteinogenic amino-acid derivative that is norvaline (2-aminopentanoic acid) in which a hydrogen at position 3 is replaced by a hydroxy group. | [Biochem/physiol Actions]
3-Hydroxynorvaline (HNV) is a microbial, α amino acid threonine analogue which has antiviral activity (herpes virus) and is toxic to mammalian cells (embryotoxic and teratogenic) presumably via incorporation into proteins. 3-Hydroxynorvaline may be used as an unnatural amino acid to study the fidelity of protein translation at the level of acyl-tRNA editing. 3-Hydroxynorvaline may also be used to study enzymes and molecules involved in threonine metabolism. |
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