| Chemical Properties | Back Directory | [Boiling point ]
579.2±60.0 °C(Predicted) | [density ]
1.139±0.06 g/cm3(Predicted) | [solubility ]
DMSO: soluble; Ethanol: soluble | [form ]
A crystalline solid | [pka]
1.11±0.50(Predicted) |
| Hazard Information | Back Directory | [Description]
Phospho-ginkgolic acid is an agonist of sphingosine-1-phosphate receptor 1 (S1P1).1 Phospho-ginkgolic acid (10 μM) induces S1P1 receptor internalization and increases ERK phosphorylation in a concentration-dependent manner in CHO cells expressing S1P1. | [Uses]
Ginkgolic acid 2-phosphate is a potent sphingosine 1-phosphate agonist. Ginkgolic acid 2-phosphate induces ERK phosphorylation. Ginkgolic acid 2-phosphate interactes with S1P1[1]. | [References]
1. Swamy, M.M.M., Murai, Y., Ohno, Y., et al. Structure-inspired design of a sphingolipid mimic sphingosine-1-phosphate receptor agonist from a naturally occurring sphingomyelin synthase inhibitor Chem. Commun. 54(90),12758-12761(2018). |
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Biorbyt Ltd.
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