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228418-81-3

228418-81-3 Structure

228418-81-3 Structure
IdentificationBack Directory
[Name]

(±)-LY 426965 dihydrochloride
[CAS]

228418-81-3
[Synonyms]

(±)-LY426965 (hydrochloride)
(±)-LY 426965 dihydrochloride
[Molecular Formula]

C28H39ClN2O2
[MDL Number]

MFCD10565912
[MOL File]

228418-81-3.mol
[Molecular Weight]

471.08
Chemical PropertiesBack Directory
[solubility ]

DMSO: 25 mg/ml
[form ]

A solid
Hazard InformationBack Directory
[Description]

(±)-LY426965 is a racemic mixture of the serotonin (5-HT) receptor subtype 5-HT1A antagonist (S)-(+)-LY426965 and (R)-(–)-LY426965.1,2
[Uses]

(±)-LY-426965 dihydrochloride is a racemate of LY-426965 (HY-117799). LY426965 is a potent 5-HT1A receptor antagonist[1].
[References]

1. Kaplin, A.I., Hendrix, C.W., and Rahn, K.A. Methods for reducing anxiety and impulsivity in subjects initiating treatment with serotonin reuptake inhibitors WO2014209991A1,(2014).
2. Denmark, S.E., and Fu, J. Asymmetric construction of quaternary centers by enantioselective allylation: Application to the synthesis of the serotonin antagonist LY426965 Org. Lett. 4(11),1951-1953(2002).
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