Chemical Properties | Back Directory | [Boiling point ]
593.0±50.0 °C(Predicted) | [density ]
1.69±0.1 g/cm3(Predicted) | [storage temp. ]
Store at -20°C | [solubility ]
DMSO: 125 mg/mL (466.10 mM) | [form ]
Solid | [pka]
-10.35±0.20(Predicted) | [color ]
Light yellow to yellow |
Hazard Information | Back Directory | [Uses]
NQO1 substrate acts as an efficient NQO1 substrate and may be a new option for the treatment of NQO1-overexpresssing drug-resistant NSCLC[1]. | [storage]
Store at -20°C | [References]
[1] Wu X, et al. Discovery of Nonquinone Substrates for NAD(P)H: Quinone Oxidoreductase 1 (NQO1) as Effective Intracellular ROS Generators for the Treatment of Drug-Resistant Non-Small-Cell Lung Cancer. J Med Chem. 2018 Dec 27;61(24):11280-11297. DOI:10.1021/acs.jmedchem.8b01424 |
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