| Identification | Back Directory | [Name]
TRPV4 agonist-1 | [CAS]
2314467-60-0 | [Synonyms]
TRPV4 agonist
RPV4 agonist-1
TRPV4 agonist-1
OUN67600(TRPV4 agonist-1) | [Molecular Formula]
C25H23ClF2N4O2 | [MDL Number]
MFCD31813757 | [MOL File]
2314467-60-0.mol | [Molecular Weight]
484.93 |
| Hazard Information | Back Directory | [Description]
OUN67600, is a Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonist as Regulators of Chondrogenic Differentiation. OUN67600 was first reported by Atobe et al (compound 36 in J Med Chem. 2019 Feb 14;62(3):1468-1483). This product has no formal name at the moment. | [Uses]
TRPV4 agonist-1 is a transient receptor potential vanilloid 4 (TRPV4) agonist with an EC50 of 60 nM in the hTRPV4 Ca2+ assay[1]. | [storage]
Store at -20°C | [References]
[1] Atobe M, et al. Discovery of Novel Transient Receptor Potential Vanilloid 4 (TRPV4) Agonists as Regulators of Chondrogenic Differentiation: Identification of Quinazolin-4(3 H)-ones and in Vivo Studies on a Surgically Induced Rat Model of Osteoarthritis. J Med Chem. 2019 Feb 14;62(3):1468-1483. DOI:10.1021/acs.jmedchem.8b01615 |
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| Company Name: |
InvivoChem
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13549236410 |
| Website: |
https://www.invivochem.cn/ |
| Company Name: |
Biorbyt Ltd.
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+44 (0)1223 859 353 |
| Website: |
www.biorbyt.com |
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