| Identification | Back Directory | [Name]
Olean-12-en-16-one, 3-[(6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranosyl)oxy]-11,15,23,28-tetrahydroxy-, (3β,4α,15α)- | [CAS]
2319668-87-4 | [Synonyms]
Olean-12-en-16-one, 3-[(6-deoxy-3-O-β-D-glucopyranosyl-β-D-galactopyranosyl)oxy]-11,15,23,28-tetrahydroxy-, (3β,4α,15α)- | [Molecular Formula]
C42H68O15 | [MOL File]
2319668-87-4.mol | [Molecular Weight]
812.99 |
| Hazard Information | Back Directory | [Uses]
Tibesaikosaponin V (TKV) is a triterpene diglycoside, which can be isolated from the methanol extract of the roots of Bupleurum chinense DC.. Tibesaikosaponin V inhibits lipid accumulation and triacylglycerol content occurred without cytotoxicity to adipocytes. Tibesaikosaponin V suppresses the mRNA expression of nuclear transcription factors, such as peroxisome proliferator-activated receptor γ (PPARγ) and CCAAT/enhancer binding protein α (C/EBPα). Tibesaikosaponin V inhibits 3T3-L1 preadipocyte differentiation. Tibesaikosaponin V can be used fro research of obesity and its associated metabolic disorders[1]. | [IC 50]
PPARγ | [References]
[1] Feng Y, et al. A new triterpene diglycoside from the roots of Bupleurum chinense DC. and its inhibitory effect on adipogensis in 3T3-L1 cells[J]. Medicinal Chemistry Research, 2019, 28: 239-245. |
|
| Company Name: |
Mensura Group Limited
|
| Telephone: |
17318633522 |
| Website: |
www.chemicalbook.com/supplier/132157015/ |
| Company Name: |
Mensura Group Limited
|
| Telephone: |
18780014153 |
| Website: |
www.chemicalbook.com/manufacturer/mensura%20group%20limited/ |
|