Identification | Back Directory | [Name]
Methanone, [1,1'-biphenyl]-3-yl(4-methyl-1-piperidinyl)- | [CAS]
2322051-02-3 | [Synonyms]
Cas9-IN-3 1,1'-Biphenyl]-3-yl(4-methyl-1-piperidinyl)methanone Methanone, [1,1'-biphenyl]-3-yl(4-methyl-1-piperidinyl)- | [Molecular Formula]
C19H21NO | [MOL File]
2322051-02-3.mol | [Molecular Weight]
279.38 |
Chemical Properties | Back Directory | [Boiling point ]
459.0±24.0 °C(Predicted) | [density ]
1.075±0.06 g/cm3(Predicted) | [form ]
Liquid
(Density: 1.075±0.06 g/cm3) | [pka]
-1.49±0.40(Predicted) | [color ]
Colorless to light yellow |
Hazard Information | Back Directory | [Uses]
Cas9-IN-3 is a potent Cas9 inhibitor (IC50=28 μM)[1]. | [References]
[1] Lee SW, et al. Identification and Optimization of Novel Small-Molecule Cas9 Inhibitors by Cell-Based High-Throughput Screening. J Med Chem. 2022;65(4):3266-3305. DOI:10.1021/acs.jmedchem.1c01834 |
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