| Chemical Properties | Back Directory | [Boiling point ]
739.5±60.0 °C(predicted) | [density ]
1.339±0.06 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted) | [pka]
11.27±0.29(predicted) |
| Hazard Information | Back Directory | [Uses]
TBAJ-5307 is a broad spectrum anti-non-tuberculous mycobacteria inhibitor that can target the FO-domain of the engine and preventing rotation and proton-translocation. TBAJ-5307 inhibits non-tuberculous mycobacteria in vitro and in vivo[1]. | [References]
[1] Ragunathan P, et, al. High efficacy of the F-ATP synthase inhibitor TBAJ-5307 against non-tuberculous mycobacteria in vitro and in vivo. J Biol Chem. 2024 Jan 2:105618. DOI:10.1016/j.jbc.2023.105618 |
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