| Identification | Back Directory | [Name]
3-Quinolineethanol, 6-bromo-α-(2,6-dimethoxy-4-pyridinyl)-α-[2-(dimethylamino)ethyl]-2-methoxy-β-(2,3,6-trimethoxy-4-pyridinyl)-, (αS,βR)- | [CAS]
2332841-25-3 | [Synonyms]
TBAJ-876
3-Quinolineethanol, 6-bromo-α-(2,6-dimethoxy-4-pyridinyl)-α-[2-(dimethylamino)ethyl]-2-methoxy-β-(2,3,6-trimethoxy-4-pyridinyl)-, (αS,βR)- | [Molecular Formula]
C31H37BrN4O7 | [MOL File]
2332841-25-3.mol | [Molecular Weight]
657.55 |
| Chemical Properties | Back Directory | [Boiling point ]
757.1±60.0 °C(Predicted) | [density ]
1.335±0.06 g/cm3(Predicted) | [form ]
Solid | [pka]
11.20±0.29(Predicted) | [color ]
White to off-white |
| Hazard Information | Back Directory | [Uses]
TBAJ-876 is the inhibitor of mycobacterium tuberculosis. TBAJ-876 is the analogue of the anti-tuberculosis agent Bedaquiline. TBAJ-876 has the potential for the research of tuberculosis[1]. | [References]
[1] Sutherland HS, et al. Variations in the C-unit of bedaquiline provides analogues with improved biology and pharmacology. Bioorg Med Chem. 2020;28(1):115213. DOI:10.1016/j.bmc.2019.115213 |
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