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RXFP3/4 agonist 1 is an agonist of relaxin family peptide 3/4 receptor (RXFP3/4), with EC50s of 82/2 nM, respectivley. RXFP3/4 agonist 1 increases food intake in rats[1]. | [References]
[1] DeChristopher B, et al. Discovery of a small molecule RXFP3/4 agonist that increases food intake in rats upon acute central administration. Bioorg Med Chem Lett. 2019 Apr 15;29(8):991-994. DOI:10.1016/j.bmcl.2019.02.013 |
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