| Identification | Back Directory | [Name]
Flurescein-PEG5-NHS ester | [CAS]
2353409-62-6 | [Synonyms]
Fluorescein-PEG5-NHS
5-FITC-PEG5-NHS ester
Flurescein-PEG5-NHS ester
Fluorescein-PEG5-NHS ester
4,7,10,13,16-Pentaoxa-19-azaeicosanoic acid, 20-[(3',6'-dihydroxy-3-oxospiro[isobenzofuran-1(3H),9'-[9H]xanthen]-5-yl)amino]-20-thioxo-, 2,5-dioxo-1-pyrrolidinyl ester | [Molecular Formula]
C38H41N3O14S | [MDL Number]
MFCD31811456 | [MOL File]
2353409-62-6.mol | [Molecular Weight]
795.81 |
| Hazard Information | Back Directory | [Description]
Fluorescein-PEG5-NHS ester is a fluorescein labeled PEG linker containing a NHS group, which enables labeling for antibodies and other purified proteins at primary amines (lysine side chains). The hydrophilic PEG spacer arm increases solubility in aqueous media. | [Uses]
Fluorescein-PEG5-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. | [IC 50]
PEGs | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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