| Identification | Back Directory | [Name]
1H-Isoindol-1-one, 7-(dimethylamino)-2,3-dihydro-4-[4-methyl-6-[[[6-(trifluoromethyl)-3-pyridinyl]methyl]amino]-3-pyridinyl]- | [CAS]
2361378-89-2 | [Synonyms]
CSF1R-IN-14
1H-Isoindol-1-one, 7-(dimethylamino)-2,3-dihydro-4-[4-methyl-6-[[[6-(trifluoromethyl)-3-pyridinyl]methyl]amino]-3-pyridinyl]- | [Molecular Formula]
C23H22F3N5O | [MOL File]
2361378-89-2.mol | [Molecular Weight]
441.45 |
| Hazard Information | Back Directory | [Uses]
CSF1R-IN-14 is an isoindolinone derivative compound. CSF1R-IN-14 is a potent inhibitor of CSF1R. Colony stimulating factor 1 (CSF-1, also known as macrophage colony stimulating factor, M-CSF) is an important growth factor that controls bone marrow progenitor cells, monocytes, macrophages, and giants. CSF1R-IN-14 has the potential for the research of cancer diseases (extracted from patent WO2019134662A1, compound 1)[1]. | [References]
[1] Wenyuan Qian, et al. Heterocyclic compound as csf-1r inhibitor and use thereof. Patent WO2019134662A1. |
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