| Identification | Back Directory | [Name]
2,8-DIAZA-SPIRO[4.5]DECANE-8-CARBOXYLIC ACID TERT-BUTYL ESTER | [CAS]
236406-39-6 | [Synonyms]
D67158
8-Boc-2,8-diaza-spiro[4.5...
8-Boc-2,8-Diazaspiro[4.5]decane
8-N-Boc-2,8-diaza-spiro[4.5]decane
tert-Butyl 3,8-diazaspiro[4.5]decane-8-carboxylate
TERT-BUTYL 2,8-DIAZASPIRO[4.5]DECANE-8-CARBOXYLATE
tert-butyl 2,8-diazaspiro[4.5]decane-8-carboxylate(SALTDATA: FREE)
2,8-Diazaspiro[4.5]decane-8-carboxylic acid tert-butyl ester - D5994
2,8-Diazaspiro[4.5]decane-8-carboxylic acid, 1,1-dimethylethyl ester
2,8-Diazaspiro[4.5]decane-8-carboxylic acid tert-butyl ester hydrochloride
2,8-Diazaspiro[4.5]decane-8-carboxylicacid, 1,1-diMethylethyl ester hydrochloride | [Molecular Formula]
C13H24N2O2 | [MDL Number]
MFCD09608078 | [MOL File]
236406-39-6.mol | [Molecular Weight]
240.34 |
| Chemical Properties | Back Directory | [Boiling point ]
337.0±35.0 °C(Predicted) | [density ]
1.07±0.1 g/cm3(Predicted) | [storage temp. ]
Keep in dark place,Sealed in dry,2-8°C | [pka]
11.04±0.20(Predicted) | [Appearance]
White to off-white Solid | [InChI]
InChI=1S/C13H24N2O2/c1-12(2,3)17-11(16)15-8-5-13(6-9-15)4-7-14-10-13/h14H,4-10H2,1-3H3 | [InChIKey]
MGHFVXFMQGQAKJ-UHFFFAOYSA-N | [SMILES]
C1C2(CCN(C(OC(C)(C)C)=O)CC2)CCN1 |
| Hazard Information | Back Directory | [Chemical Properties]
White solid | [Uses]
tert-Butyl 2,8-Diazaspiro[4.5]decane-8-carboxylate is used in preparation of substituted aminoquinolones as DGKα inhibitors for immune activation. | [Synthesis]
The synthetic route for tert-butyl 2,8-diazaspiro[4.5]decane-8-carboxylate was as follows: the intermediate tert-butyl 4-(2,2-dimethyl-4,6-dicarbonyl-1,3-dioxin-5-ylidene)piperidine-1-carboxylate was subjected to Michell addition with nitromethane to give |
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