2364479-10-5

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2364479-10-5 Structure

Identification	Back Directory
[Name] 7-Quinolinecarbonitrile, 1-[2-[4-[[(3,4-dihydro-3-oxo-2H-1,4-benzothiazin-6-yl)methyl]amino]-1-piperidinyl]ethyl]-1,2-dihydro-2-oxo-
[CAS] 2364479-10-5
[Synonyms] Antibacterial agent 236 7-Quinolinecarbonitrile, 1-[2-[4-[[(3,4-dihydro-3-oxo-2H-1,4-benzothiazin-6-yl)methyl]amino]-1-piperidinyl]ethyl]-1,2-dihydro-2-oxo-
[Molecular Formula] C26H27N5O2S
[MOL File] 2364479-10-5.mol
[Molecular Weight] 473.59

Chemical Properties	Back Directory
[Boiling point ] 705.3±60.0 °C(predicted)
[density ] 1.38±0.1 g/cm3(Temp: 20 °C; Press: 760 Torr)(predicted)
[pka] 12.86±0.20(predicted)

Hazard Information	Back Directory
[Uses] Antibacterial agent 236 (Compound 4l) is an orally active inhibitor for DNA gyrase and topoisomerase IV (IC50 is 3.2 and 300 nM in Staphylococcus aureus), and exhibits board-spectrum antibacterial activity. Antibacterial agent 236 exhibits good pharmacokinetic properties in mice[1].
[References] [1] Desai J, et al., Discovery of aminopiperidine based potent & novel topoisomerase inhibitor with broad spectrum anti-bacterial activity. Bioorg Med Chem Lett. 2024 Oct 1;111:129911. DOI:10.1016/j.bmcl.2024.129911

2364479-10-5 suppliers list

Company Name:	Shanghai Beckham Medical Technology Co., Ltd
Tel:	021-13816613772 13816613772
Website:	www.chemicalbook.com/ShowSupplierProductsList16976/0_EN.htm

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