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23661-03-2

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23661-03-2 Structure

23661-03-2 Structure
IdentificationBack Directory
[Name]

N6-(3-Trifluoromethylbenzyl)adenosine
[CAS]

23661-03-2
[Synonyms]

Antiviral agent 24
N-(3-trifluoromethylbenzyl)adenosine
N6-(3-Trifluoromethylbenzyl)adenosine
Adenosine, N-?[[3-?(trifluoromethyl)?phenyl]?methyl]?-
[Molecular Formula]

C18H18F3N5O4
[MOL File]

23661-03-2.mol
[Molecular Weight]

425.36
Chemical PropertiesBack Directory
[form ]

Solid
[color ]

White to off-white
Hazard InformationBack Directory
[Uses]

Antiviral agent 24 is a potent antiviral agent with EC50 values of 0.101, 19.9, 91.2 μM for EV71, CVA21, EV68, respectively. Antiviral agent 24 inhibits METTL3/METTL14 activity in a dose-dependent manner[1].
[References]

[1] Salerno M, et al. Rational design of novel nucleoside analogues reveals potent antiviral agents for EV71. Eur J Med Chem. 2022 Nov 24;246:114942. DOI:10.1016/j.ejmech.2022.114942
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