| Identification | Back Directory | [Name]
VICENIN | [CAS]
23666-13-9 | [Synonyms]
Vicenin-2
Vicenin-II
Apigenin 6,8-diglucoside
Apigenin 6,8-C-diglucoside
6,8-Di-C-β-D-glucopyranosylapigenin
Apigenin 6,8-C-di-β-D-glucopyranoside
Apigenin 6,8-di-C-glucoside (Vicenin-2)
4H-1-Benzopyran-4-one,6,8-di-b-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-
6,8-Di(β-D-glucopyranosyl)-5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-1-benzopyran-4-one
2-(4-Hydroxyphenyl)-5,7-dihydroxy-6,8-bis(β-D-glucopyranosyl)-4H-1-benzopyran-4-one
4H-1-Benzopyran-4-one, 6,8-di-β-D-glucopyranosyl-5,7-dihydroxy-2-(4-hydroxyphenyl)-
5,7-Dihydroxy-2-(4-hydroxyphenyl)-6,8-bis[(2S,3R,4R,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl)oxan-2-yl]chromen-4-one | [Molecular Formula]
C27H30O15 | [MDL Number]
MFCD08458851 | [MOL File]
23666-13-9.mol | [Molecular Weight]
594.52 |
| Chemical Properties | Back Directory | [Melting point ]
>250 °C (decomp) | [Boiling point ]
974.7±65.0 °C(Predicted) | [density ]
1.758±0.06 g/cm3(Predicted) | [storage temp. ]
Hygroscopic, -20°C Freezer, Under inert atmosphere | [solubility ]
Methanol (Slightly, Heated, Sonicated), DMSO (Slightly) | [form ]
Solid | [pka]
5.68±0.40(Predicted) | [color ]
Light Yellow to Yellow | [Water Solubility ]
sparingly soluble in water | [Stability:]
Hygroscopic | [InChIKey]
FIAAVMJLAGNUKW-YFDIWHCFNA-N |
| Hazard Information | Back Directory | [Chemical Properties]
White crystalline powder, soluble in organic solvents such as methanol, ethanol, and DMSO, derived from Desmodium sibiricum. | [Uses]
Vicenin 2 (CAS# 23666-13-9) is a biologically active compound extracted from Hypericum salsugineum and displays significant anti-cancer effects on breast carcinoma cell lines. | [Definition]
ChEBI: Isovitexin 8-C-beta-glucoside is a C-glycosyl compound that is isovitexin in which the hydrogen at position 8 is replaced by a beta-D-glucosyl residue. It has a role as a metabolite. It is a trihydroxyflavone and a C-glycosyl compound. It is functionally related to an isovitexin. | [Synthesis]
A method for simultaneous isolation of schaftoside, vicenin-2, and ecdysterone from Sagina japonica:
1. Ethanol extraction, followed by solvent partitioning to obtain an n-butanol extract.
2. The extract is fractionated on an AB-8 macroporous resin | [in vivo]
Vicenin 2 (50 mg/kg; orally administration; for 7 days) effectively reduces the MPO activity, attenuates the expression of pro-inflammatory cytokines and key inflammatory markers, in DSS-induced colitis mice[3]. | Animal Model: | Male C57BL/6J mice (25 g) treated with Dextran sulfate sodium (DSS)[3] | | Dosage: | 50 mg/kg | | Administration: | Orally administration; for 7 days | | Result: | Effectively suppressed DSS-induced colitis by attenuating expressions of key inflammatory mediators. |
| [storage]
4°C, protect from light |
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