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2368978-96-3

2368978-96-3 Structure

2368978-96-3 Structure
IdentificationBack Directory
[Name]

Trx-red
[CAS]

2368978-96-3
[Synonyms]

Trx-red
NBL-SS perchlorate
Trx-red(Synonyms: NBL-SS perchlorate)
[Molecular Formula]

C29H32ClN3O12S2
[MDL Number]

MFCD34471120
[MOL File]

2368978-96-3.mol
[Molecular Weight]

714.15
Chemical PropertiesBack Directory
[form ]

Liquid
[color ]

Purple to purplish red
Hazard InformationBack Directory
[Uses]

Trx-red (NBL-SS perchlorate) is a red-emitting fluorescent probe derivatized from the nile blue fluorophore. Trx-red is used for selectively imaging thioredoxin (Trx) in live cells and in vivo (λex=615 nm, λem=661 nm)[1].
[in vivo]

Trx-red (NBL-SS; 10 μM; 30 min) is also suitable to image thioredoxin in 6 day-old zebrafish larvae[1].

[References]

[1] Huiyi Jia, et al. Fluorophore-Dependent Cleavage of Disulfide Bond Leading to a Highly Selective Fluorescent Probe of Thioredoxin. Anal Chem. 2019 Jul 2;91(13):8524-8531. DOI:10.1021/acs.analchem.9b01779
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