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2374772-60-6

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2374772-60-6 Structure

2374772-60-6 Structure
IdentificationBack Directory
[Name]

J-1048
[CAS]

2374772-60-6
[Synonyms]

J-1048
Hazard InformationBack Directory
[Uses]

J-1048 is an activin receptor-like kinase 5 (ALK5) inhibitor. J-1048 can inhibit TAA-induced liver fibrosis in mice by explicitly blocking the TGF-β/Smad signaling pathway[1].
[References]

[1] Yang HX, et al. Synthesis of and anti-fibrotic effect of pyrazole derivative J-1048: Inhibition of ALK5 as a novel approach to liver fibrosis targeting inflammation. Bioorg Chem. 2023 Oct;139:106723. DOI:10.1016/j.bioorg.2023.106723
2374772-60-6 suppliers list
Company Name: TargetMol Chemicals Inc.
Tel: +17819995354 , +17819995354
Website:
Company Name: TargetMol Chemicals Inc.  
Tel: 15002134094
Website: https://www.targetmol.cn/
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