ChemicalBook--->CAS DataBase List--->23749-58-8

23749-58-8

23749-58-8 Structure

23749-58-8 Structure
IdentificationBack Directory
[Name]

BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
[CAS]

23749-58-8
[Synonyms]

luminor2
luminogren
luminophor2
Yellow 2GF
yellow-green490rt
Solvent Yellow 184
LABOTEST-BB LT00007121
luminoryellowgreen490rt
naphthoylenebenzimidazole
luminoforyellow-green490rt
1,8-Naphthoylene-1',2'-benzimidazole
7H-BENZIMIDAZO[2,1-A]BENZ[DE]ISOQUINOL
7H-7a,12-Diazaindeno[2,1-a]phenalene-7-one
7a,12-Diazaindeno[2,1-a]phenalene-7(7aH)-one
BENZIMIDAZO[2,1-A]BENZ[D,E]ISOQUINOLION-7-ONE
7h-benzimidazo(2,1-a)benz(de)isoquinolin-7-one
7H-Benzimidazol[2,1-a]benz[de]isochinolin-7-on
7H-Benzimidazo[2,1-a]benz[de]-7-isoquinolinone
7H-Benzimidazo[2,1-a]benzo[de]isoquinolin-7-one
Benzimidazo[2,1-a]benz[d,e]isoquinolion-7-one 98%
BENZO(DE)BENZO(4,5)IMIDAZO(2,1-A)ISOQUINOLIN-7-ONE
7H-Benzimidazo[2,1-a]benz[d,e]isoquinolin-7-one98%
7H-Benzimidazo[2,1-a]benz[d,e]isoquinolin-7-one 98%
7H-Benzo[de]benzo[4,5]imidazo[2,1-a]isoquinolin-7-one
1,8-naphthoilene-1,2-benzimidazole (Luminor yellow-green 490 RT)
[EINECS(EC#)]

245-865-7
[Molecular Formula]

C18H10N2O
[MDL Number]

MFCD00056826
[MOL File]

23749-58-8.mol
[Molecular Weight]

270.28
Chemical PropertiesBack Directory
[Melting point ]

189 °C
[Boiling point ]

613.6±38.0 °C(Predicted)
[density ]

1.40±0.1 g/cm3(Predicted)
[form ]

powder
[pka]

2.05±0.20(Predicted)
[color ]

Bright yellow
[InChI]

InChI=1S/C18H10N2O/c21-18-13-8-4-6-11-5-3-7-12(16(11)13)17-19-14-9-1-2-10-15(14)20(17)18/h1-10H
[InChIKey]

NZBSAAMEZYOGBA-UHFFFAOYSA-N
[SMILES]

C12=NC3=CC=CC=C3N1C(=O)C1=CC=CC3=CC=CC2=C13
Safety DataBack Directory
[Symbol(GHS) ]

GHS hazard pictograms
GHS07
[Signal word ]

Warning
[Hazard statements ]

H315-H319-H335
[Precautionary statements ]

P261-P264-P271-P280-P312
[HS Code ]

2933998090
Hazard InformationBack Directory
[Uses]

AHR agonist 3 is an aryl hydrocarbon receptor (AhR) agonist, that can induces cell cycle arrest or apoptosis via activation of tumor-suppressive transcriptional programs. AHR agonist 3 inhibits triple-negative breast cancer (TNBC) stem cell growth via AhR while exhibits minimal cytotoxicity against normal human primary cells and can be used for cancer research[1].
[Properties and Applications]

TEST ITEMS

SPECIFICATION

APPEARANCE

YELLOW POWDER

SHADE

GREENISH

HEAT RESISTANCE

260 °C min

LIGHT FASTNESS

5-6

ACID RESISTANCE

5

ALKALI RESISTANCE

5

WATER RESISTANCE

5

DENSITY

1.20 g/cm 3

RESIDUE ON 80 MESH

5.0% max

WATER SOLUBLE

1.0% max

VOLATITE 105 °C

1.0% max

TINTING STRENGTH

100-105 %

WEIGHT METAL TOTAL

50ppm max

[References]

[1] Elson DJ, et.al. Induction of Aryl Hydrocarbon Receptor-Mediated Cancer Cell-Selective Apoptosis in Triple-Negative Breast Cancer Cells by a High-Affinity Benzimidazoisoquinoline. ACS Pharmacol Transl Sci. 2023 Jun 7;6(7):1028-1042. DOI:10.1021/acsptsci.2c00253
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