| Chemical Properties | Back Directory | [solubility ]
DMSO : 100 mg/mL (78.78 mM; Need ultrasonic) | [form ]
Solid | [color ]
White to off-white | [InChIKey]
MGAQCNKHLTVSCR-UHFFFAOYSA-N | [SMILES]
O(N1C(CCC1=O)=O)C(=O)CCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCOCCN=[N+]=[N-] |
| Hazard Information | Back Directory | [Description]
Azido-PEG24-NHS ester is a monodisperse, high purity PEG linker. The azide group enables Click Chemistry. The NHS ester can be used to label the primary amines (-NH2) of proteins, oligonucleotides, and other amine-containing biomolecules. The hydrophilic PEG spacer adds to the water solubility of this reagent. | [Uses]
Azido-PEG24-NHS ester is a PEG-based PROTAC linker that can be used in the synthesis of PROTACs[1]. Azido-PEG24-NHS ester is a click chemistry reagent, it contains an Azide group and can undergo copper-catalyzed azide-alkyne cycloaddition reaction (CuAAc) with molecules containing Alkyne groups. It can also undergo strain-promoted alkyne-azide cycloaddition (SPAAC) reactions with molecules containing DBCO or BCN groups. | [Application]
Azido-PEG24-NHS ester (CAS 2375600-46-5) is a high-purity PEG derivative widely used in the development of novel drug conjugates and for bio-conjugation reactions; it is also employed as a surface modifier in drug delivery systems and biomedical applications. | [IC 50]
PEGs; Alkyl/ether | [References]
[1] An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562 DOI:10.1016/j.ebiom.2018.09.005 |
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| Company Name: |
Borenpharm Co., Ltd
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| Telephone: |
027-65563561 13026317987; |
| Website: |
http://www.borenpharm.com |
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